What doses of Plaquenil doses may cause toxicity/maculopathy? by Dev1 | Sep 6, 2023 | Bookmarking Post, CLINICAL DISTINCTIONS | 0 comments Bookmark Please login to bookmarkClosePlease login Chloroquine: 3mg/kg/day for 5 years (300 grams, total cumulative dose) Hydroxychloroquine: 6.5mg/kg/day for 5 years (700 grams, total cumulative dose). The daily dose should not exceed 400 mg.